
SI-2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Si-2 is a potent inhibitor of steroid receptor coactivator-3 (SRC-3) .1 It blocks MDA-MB-468 cell growth with an IC50 = 3.4 nM without effecting normal cells.1 It significantly inhibited breast cancer cell growth in an orthotopic MDA-MD-468 mouse model. Treatment of MCF-7 or triple negative MDA-MB-231 cells with SI-2 resulted in inhibition of proliferation and breast cancer stem cell (CSC) tumorsphere formation.2 CSC markers CD44+/CD24-/1o and aldehyde dehydrogenase (ALDH) were also reduced indicating that SI-2 can selectively interfere with the TIC/CSC state in breast cancer cells.2,3
Unconjugated
Pale orange solid
-20°C
Beschrijving
SI-2 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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