SIAH2 Antilichaam - middengebied HRP (ARP33290_P050-HRP)

Siah E3 ubiquitin protein ligase 2

HSiah2

6478

O43255

NP_005058

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SIAH2

SIAH2 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

EGLN3; XAF1; HIPK2; UBE2D1; UBE2L6; SIAH2; UBE2D3; UBC; PPP1R13B; TP53BP2; NFE2L2; USP19; AR; UBE2I; STAT3; MYD88; EEF1D; CCBE1; SETD2; HIPK3; TNK2; KAT5; KAT2B; UBE2D2; TPX2; PML; ATN1; PSMD4; PPP1R12A; EGLN2; SH3RF1; EGLN1; DYRK2; PPP1CC; AFF1; DCC; CEB

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

SIAH2 is supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

34kDa

Rott, R., (2008) J. Biol. Chem. 283 (6), 3316-3328

Wet Ice

324

SIAH2

SIAH2

Rabbit

E3 ubiquitin-protein ligase SIAH2

NM_005067

AVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYR