Sifuvirtide (acetaat)

Sifuvirtide (SFT) acetate is a potent HIV fusion inhibitor. Sifuvirtide acetate inhibits HIV-1 mediated cell fusion in a dose-dependent manner and is highly potent against infection by primary and laboratory-adapted HIV-1 isolates of multiple genotypes. Sifuvirtide acetate can be used in the research of anti-HIV drugs[1].

SFT (acetate)

12352209

HIV

Anti-infection

Infection

99.82

O=C(C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCC(O)=O)=O)CC(C)C)=O)CC(C)C)=O)CC(O)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CC(N)=O)=O)CCCNC(N)=N)=O)CC(O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(O)=O)=O)CCC(N)=O)=O)CO)=O)CCC(O)=O)=O)CCC(O)=O)=O)CC(C)C)=O)[C@H](CC)C)=O)CCCNC(N)=N)=O)CC1=CC=C(O)C=C1)=O)[C@H](CC)C)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)[C@@H](C)O)=O)CC2=CC=C(O)C=C2)=O)CC(N)=O)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CC3=CNC4=CC=CC=C34)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CC5=CNC6=CC=CC=C56)=O)CO.CC(O)=O.[x]

C203H309N59O72.xC2H4O2

4727.98 (free base)

[1]Wang R R, et al. Sifuvirtide, a potent HIV fusion inhibitor peptide[J]. Biochemical and biophysical research communications, 2009, 382 (3) : 540-544.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P10517A/Sifuvirtide-acetate-SDS-MedChemExpress.pdf

Peptides

No Development Reported