Sigmoïdin B
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Sigmoidin B, a prenylated flavanone, is a selective 5-lipoxygenase inhibitor. Sigmoidin B is a potent scavenger of the DPPH radical. Sigmoidin B has antigenotoxic activity that inhibits genotoxicity induced by Aflatoxin B1 , with an IC50 of 18.7 μg/mL. Sigmoidin B has anti-inflammatory activity and antioxidant properties[1][2].
87746-47-2
12352005
Lipoxygenase
Metabolic Enzyme/Protease
Metabolic Disease; Inflammation/Immunology
O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(C/C=C(C)\C)=C(C(O)=C3)O)C1
C20H20O6
356.37
[1]Zarev Y, et al. Antigenotoxic prenylated flavonoids from stem bark of Erythrina latissima. Phytochemistry. 2017 Sep;141:140-146. |[2]Njamen D, et al. Anti-inflammatory activities of two flavanones, sigmoidin A and sigmoidin B, from Erythrina sigmoidea. Planta Med. 2004 Feb;70 (2) :104-7.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N11845/
Natural Products
No Development Reported
5-LOX
Beschrijving
Sigmoidin B, a prenylated flavanone, is a selective 5-lipoxygenase inhibitor. Sigmoidin B is a potent scavenger of the DPPH radical. Sigmoidin B has antigenotox
Specificaties
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