Signaaltransducer en activator van transcriptie 5A Adenovirus (Ad-STAT5)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Stats (signal transducers and activators of transcription) are tyrosine phosphorylated transcription factors activated by JAK family kinases. Various ligands, including interferons and growth factors, induce activation of the JAK kinases, which induce Stat activation. Stat1 and Stat2 are induced by IFN-alpha and form a heterodimer that is part of the ISGF-3 transcription factor complex. Stat3 (alpha) is activated by EGF and IL-6. Stat3 (alpha) is activated by EGF. Highest expression of Stat4 is observed in the testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 can be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways. Stat-1 and Stat-3 bind the serum-inducible element (SIE) and GAS/ISRE elements are also known to be STAT-binding sites.
Signal transducer and activator of transcription 5A Adenovirus
41106621
3822190000
Pre-Made
Dry Ice
-80C
12 Months
Ad-STAT5
Human Adenovirus Type5 (dE1/E3)
CMV (ubiquitous)
DMEM, 2% BSA, 2.5% Glycerol
1x10^10 PFU/ml
Beschrijving
Stats (signal transducers and activators of transcription) are tyrosine phosphorylated transcription factors activated by JAK family kinases. Various ligands, i
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