SIK2 Antilichaam - N-terminalgebied: FITC (ARP62714 P050-FITC)

Salt-inducible kinase 2

QIK, SIK-2, SNF1LK2, LOH11CR1I

23235

Q9H0K1

NP_056006

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

SIK2 phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. It inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.

GABARAPL2; YWHAZ; YWHAE; VCP; HSPA4; HDAC5; CEP250; UBC; APP; BMH1; CRTC2; YWHAQ; PRKAA1; IRS1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

SIK2 is supported by BioGPS gene expression data to be expressed in HeLa

0.5 mg/ml

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

102kDa

Wet Ice

926

SIK2

SIK2

Rabbit

Serine/threonine-protein kinase SIK2

NM_015191

VLYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKTIESLQNKSYNHFAAIY