SILV Antilichaam - N-terminaal gebied: Biotine (ARP46802 T100-Biotine)

Premelanosome protein

P1, SI, SIL, ME20, P100, SILV, ME20M, gp100, ME20-M, PMEL17, D12S53E

6490

P40967

NP_008859

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human SILV

SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.

Biotin

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Cow: 93%; Dog: 86%; Goat: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

70kDa

Theos, A.C., (2006) Dev. Cell 10 (3), 343-354

Wet Ice

661

PMEL

PMEL

Rabbit

Melanocyte protein PMEL

NM_006928

HFLRNQPLTFALQLHDPSGYLAEADLSYTWDFGDSSGTLISRALVVTHTY