SingleFlowEx CD28 APC

CD28.2

FC (QC tested)

0.035 mg/mL

APC

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

1 vial of monoclonal antibody reagent.The content (1 mL) is sufficient for min. 100 Tests.

*Marti F, Krause A, Post NH, Lyddane C, Dupont B, Sadelain M, King PD: Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6. J Immunol. 2001 Jan 1;166 (1) :197-206. , URL: https://www.ncbi.nlm.nih.gov/pubmed/11123293?ordin, *Scharschmidt E, Wegener E, Heissmeyer V, Rao A, Krappmann D: Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling. Mol Cell Biol. 2004 May;24 (9) :3860-73. , URL: https://www.ncbi.nlm.nih.gov/pubmed/15082780?ordin, *Jeong SH, Qiao M, Nascimbeni M, Hu Z, Rehermann B, Murthy K, Liang TJ. Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates. J Virol. 2004 Jul;78 (13) :6995-7003., URL: https://www.ncbi.nlm.nih.gov/pubmed/15194776?ordin, *Nunès J, Klasen S, Ragueneau M, Pavon C, Couez D, Mawas C, Bagnasco M, Olive D: CD28 mAbs with distinct binding properties differ in their ability to induce T cell activation: analysis of early and late activation events. Int Immunol. 1993 Mar;5 (3) :311-5., URL: https://www.ncbi.nlm.nih.gov/pubmed/8385476?ordina, *Nunes J, Klasen S, Franco MD, Lipcey C, Mawas C, Bagnasco M, Olive D: Signalling through CD28 T-cell activation pathway involves an inositol phospholipid-specific phospholipase C activity. Biochem J. 1993 Aug 1;293 (Pt 3) :835-42., URL: https://www.ncbi.nlm.nih.gov/pubmed/8394695?ordina, *Schlossman, S., et al., Eds. 1995. Leucocyte Typing V. Oxford University Press. New York., URL: , *Galea-Lauri J, Darling D, Gan SU, Krivochtchapov L, Kuiper M, Gäken J, Souberbielle B, Farzaneh F: Expression of a variant of CD28 on a subpopulation of human NK cells: implications for B7-mediated stimulation of NK cells. J Immunol. 1999 Jul 1;163 (1) :62-70., URL: https://www.ncbi.nlm.nih.gov/pubmed/10384100?ordin, *Tazi A, Moreau J, Bergeron A, Dominique S, Hance AJ, Soler P: Evidence that Langerhans cells in adult pulmonary Langerhans cell histiocytosis are mature dendritic cells: importance of the cytokine microenvironment. J Immunol. 1999 Sep 15;163 (6) :3511-5., URL: https://www.ncbi.nlm.nih.gov/pubmed/10477625?ordin, *Mary C, Coulon F, Poirier N, Dilek N, Martinet B, Blancho G, Vanhove B: Antagonist properties of monoclonal antibodies targeting human CD28: Role of valency and the heavy-chain constant domain. MAbs Jan-Feb 2013;5 (1) :47-55., URL: https://pubmed.ncbi.nlm.nih.gov/23221503/

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.