SIRT5 Antilichaam - middengebied: Biotine (ARP40126_P050-Biotine)

Sirtuin 5

SIR2L5

23408

Q9NXA8

NP_036373

Human, Mouse, Cow, Goat, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human SIRT5

SIRT5 is included in class III of the sirtuin family which ischaracterized by a sirtuin core domain. Human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in two transcript variants.

SIRT3; UBC; HECW2; APP; RELA

Biotin

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Cow: 79%; Goat: 79%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

34kDa

Chowdari, K.V., (2007) Genes Brain Behav. 6 (3), 229-239

Wet Ice

310

SIRT5

SIRT5

Rabbit

NAD-dependent protein deacylase sirtuin-5, mitochondrial

NM_012241

PICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLD