SIRT6 Mouse Monoclonal Antibody [Kloon ID: LBI1G3]

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.

Carrier-free (BSA/glycerol-free) SIRT6 mouse monoclonal antibody, clone LBI1G3

SIR2L6

Homo sapiens sirtuin 6 (SIRT6), transcript variant 1, mRNA.

51548

Q8N6T7

Unconjugated

WB 1:500~2000, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

SIRT6

https://www.ncbi.nlm.nih.gov/gene/?term=51548

https://www.uniprot.org/uniprot/Q8N6T7