SIRT7 Antilichaam - C-terminalgebied: FITC (ARP32406 P050-FITC)

Sirtuin 7

SIR2L7

51547

Q9NRC8

NP_057622

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT7

SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.

DDB1; VPRBP; APP; NOL6; YTHDC2; DDX31; RBM15; ANAPC1; NSD1; NOC3L; UBE2O; RBM25; CCAR2; CHD8; BEND3; PHRF1; DHX37; NUFIP2; CGN; XPO5; LRRC47; BIRC6; WDR18; THOC2; NUP107; REXO4; DDX24; XAB2; UGGT1; ZC3HAV1; YLPM1; NKRF; CCT5; SNW1; DHX30; DIS3; PUF60; COP

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

45kDa

Mahon, P.C., et al., (2000) Biochem. Biophys. Res. Commun. 273 (2), 793-798

Wet Ice

400

SIRT7

SIRT7

Rabbit

NAD-dependent protein deacetylase sirtuin-7

NM_016538

DVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSLCRSREE