SKF-105809
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SKF-105809 is a dual-action inhibitor of lipoxygenase and COX. SKF-105809 inhibits edema and inflammatory cell infiltration in mouse models of ear, paw, and peritoneum inflammation. SKF-105809 inhibits the production of relevant acute-phase reactive proteins in a mouse model of arthritis. SKF-105809 exhibits analgesic activity in a mouse abdominal contraction test and inhibits ulceration. SKF-105809 can be used in research on inflammatory and immune system diseases such as peritonitis and arthritis[1].
122454-69-7
12352005
COX; Lipoxygenase
Immunology/Inflammation; Metabolic Enzyme/Protease
Inflammation/Immunology
O=S(C)C1=CC=C(C2=C(C3=CC=NC=C3)N(CCC4)C4=N2)C=C1
C18H17N3OS
323.41
[1]Hanna N, et al. Pharmacological profile of SK&F 105809, a dual inhibitor of arachidonic acid metabolism. Drugs Exp Clin Res.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19086/
Reference compound1
Phase 1
Beschrijving
SKF-105809 is a dual-action inhibitor of lipoxygenase and COX. SKF-105809 inhibits edema and inflammatory cell infiltration in mouse models of ear, paw, and per
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