SKI2W Antilichaam

SKI2W (SKIV2L, Helicase-like protein), a DEVH-box protein, is a component of the SKI complex which is involved in the regulation of translation and RNA turnover (1,2) . SKI2W is a nucleolar and cytoplasmic protein that has a putative RNA helicase domain (2) . The potential roles of Ski2W on the clearance of degraded nuclear and cytoplasmic RNA raised their possibilities as susceptibility genes of systemic lupus erythematosus (3,4) .

6499

Q15477

NP_008860

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

SKI2W antibody is affinity chromatography purified via peptide column.

Cat. No. 1415 - Mouse Stomach Tissue Lysate

1 mg/mL

SKI2W antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SKI2W antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

SKI2W antibody is human, mouse and rat reactive. At least two isoforms of SKI2W are known to exist; this antibody will detect both isoforms.

SKIV2L

Cat. No. 10-801 - Human Stomach Tissue Slide

SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)

Homo sapiens

Dangel AW, Shen L, Mendoza AR, et al. Human helicase gene SKI2W in the HLA class III region exhibits striking structural similarities to the yeast antiviral gene SKI2 and to the human gene KIAA0052: emergence of a new gene family. Nucleic Acids Res. 1995; 23:2120-6.

Qu X, Yang Z, Zhang S, et al. The human DEVH-box protein Ski2w from the HLA is localized in nucleoli and ribosomes. Nucleic Acids Res. 1998; 26:4068-77.

Yang Z, Shen L, Dangel AW, et al. Four ubiquitously expressed genes, RD (D6S45) -SKI2W (SKIV2L) -DOM3Z-RP1 (D6S60E), are present between complement component genes factor B and C4 in the class III region of the HLA. Genomics 1998; 53:338-47.

Yang Z, Qu X, and Yu CY. Features of the two gene pairs RD-SKI2W and DOM3Z-RP1 located between complement component genes factor B and C4 at the MHC class III region. Front. Biosci. 2001; 6:D927-35.

Superkiller viralicidic activity 2-like, DDX13, Helicase-like protein, Helicase SKI2W, HLP, SKI2, SKIV2, SKIV2L

ELISA, WB, IHC-P, IF

67782311

Liquid