SKIIP Antibody - N-terminal regio : HRP (ARP32294 P050-HRP)

SNW domain containing 1

Bx42, SKIP, FUN20, Prp45, SKIIP, SKIP1, PRPF45, NCOA-62

22938

Q13573

NP_036377

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast

The immunogen is a synthetic peptide directed towards the N terminal region of human SKIIP

SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly (A) -binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

TRAF1; GOLGA2; KRT40; LZTS2; RINT1; TEX11; CEP55; PPIL1; TFIP11; MTUS2; IKZF1; TP53; TUBGCP3; AURKB; UBC; SUZ12; RNF2; BMI1; HECW2; HDAC11; Dlg4; TTC14; ZNF830; SNIP1; CXorf56; XAB2; CTNNBL1; SART1; NHP2L1; MFAP1; EIF4A3; MAGOH; DHX15; DDX5; PABPC1; SKIV2

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

SNW1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

61kDa

Figueroa, J.D., et al., (2004) Eur.Res.Commun.319 (4),1105-1109

Wet Ice

536

SNW1

SNW1

Rabbit

SNW domain-containing protein 1

NM_012245

RQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAIKEITEKTRVALE