SKP1 Antilichaam

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein (s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

6500

P63208

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human SKP1 (NP_733779.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

Affinity purification

SW480

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 19kDa

IgG

SKP1

A-549

HeLa

S-phase kinase-associated protein 1

Homo sapiens

SKP1, Cyclin A/CDK2-associated p19, OCP-2, OCP-II, Organ of Corti protein 2, SIII, TCEB1L, Organ of Corti protein II, p19A, SKP1A, EMC19, OCP2, p19skp1

WB, IHC

Liquid