SLAIN2 Antilichaam

SLAIN2 Antibody: SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.

57606

Q9P270

AAH40993

Human

Unconjugated

Primary Antibodies

Stem Cell

SLAIN2 Antibody is affinity chromatography purified via peptide column.

Cat. No. 11-701 - Human Testis Tissue Slide

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (100%), Mouse: (93%)

SLAIN2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SLAIN2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

64 kDa

IgG

SLAIN2 antibody is predicted not to cross-react with SLAIN1.

SLAIN2

SLAIN motif family, member 2

Homo sapiens

Hirst CE, Ng ES, Azzola L, et al. Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Dev. Biol. 2006; 293:90-103.

Van der Vaart B, Manatschal C, Grigoriev I, et al. SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J. Cell Biol. 2011; 193:1083-99.

SLAIN2 Antibody: KIAA1458, KIAA1458, SLAIN motif-containing protein 2

ELISA, IHC-P

26454712

Liquid