SLAMF9 Antilichaam

SLAMF9 Antibody: The SLAM (signalling lymphocyte activation molecule) family is a novel group of receptors on T cells in modulating the immune response. SLAMF9, also known as CD2F-10 or CD84 homolog, is a 289 amino acid type I transmembrane protein that shares 58% identity with the mouse protein. The SLAMF9 protein is predominantly expressed in hematopoietic tissues and contains an extracellular region with only two N-linked glycosylation sites, a 20-residue transmembrane region and a highly positively charged 30-residue cytoplasmic tail, suggesting a role for SLAMF9 as an adhesion molecule. SLAMF9 is thought to function in the immune response as a coreceptor for lymphocyte activation.

89886

Q96A28

NP_001139645

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Immunology

SLAMF9 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1405 - Mouse Kidney Tissue Lysate

1 mg/mL

SLAMF9 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SLAMF9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

SLAMF9 antibody is predicted to not cross-react with other SLAM protein family members.

SLAMF9

Cat. No. 10-401 - Human Kidney Tissue Slide

SLAM family member 9

Homo sapiens

Veillette A and Latour S. The SLAM family of immune-cell receptors. Curr. Opin. Immunol. 2003; 15:277-85.

Veillette A. SLAM family receptors regulate immunity with and without SAP-related adaptors. J. Exp. Med. 2004; 199:1175-8.

Fennelly JA, Tiwari B, Davis SJ, et al. CD2F-10: a new member of the CD2 subset of the immunoglobulin superfamily. Immunogenetics 2001; 53:599-602.

Detre C, Keszei M, Romero X, et al. SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions. Semin. Immunopathol. 2010; 32:157-71.

SLAMF9 Antibody: CD2F10, CD84H1, SF2001, CD2F-10, CD84-H1, CD2F10, UNQ1938/PRO4421, SLAM family member 9, CD2 family member 10

ELISA, WB, IHC-P, IF

226342990

Liquid