SLC10A2 Antilichaam

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM) ; muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG) .

6555

Q12908

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 289-348 of human SLC10A2 (NP_000443.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

HT-29

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 38kDa

IgG

WB: 1:500 - 1:2000

SLC10A2

Mouse small intestine

Mouse kidney

Rat small intestine

Rat liver

Solute carrier family 10 (sodium/bile acid cotransporter), member 2

Homo sapiens

Ileal sodium-dependent bile acid transporter, ileal apical sodium-dependent bile acid transporter, OTTHUMP00000040691, NTCP2, ISBT, solute carrier family 10 (sodium/bile acid cotransporter family), member 2, ASBT, SLC10A2

WB

Liquid