SLC29A2 Antilichaam

SLC29A2 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2) . SLC29A2 is a transmembrane glycoprotein that mediates the cellular uptake of nucleosides from the surrounding medium (3) . As a nucleoside transporter, SLC29A2 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4) .

3177

Q14542

NP_001523

Human

Unconjugated

Primary Antibodies

Cancer, Homeostasis

SLC29A2 antibody is affinity chromatography purified via peptide column.

Cat. No. 1310 - Human Bladder Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Rat: (100%)

SLC29A2 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SLC29A2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

SLC29A2 antibody is human specific. SLC29A2 antibody is predicted to not cross-react with other SLC29 proteins.

SLC29A2

Solute carrier family 29 (equilibrative nucleoside transporter), member 2

Homo sapiens

Williams JB and Lanahan AA. A mammalian delayed-early response gene encodes HNP36, a novel, conserved nucleolar protein. Biochim. Biophys. Res. Commun. 1995; 213:325-33.

Young JD, Yao SY, Baldwin JM, et al. The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29. Mol. Aspects. Med. 34:529-47.

Mangravite LM, Xiao G, and Giacomini KM. Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells. Am. J. Physiol. Renal Physiol. 284:F902-10.

Owen RP, Lagpacan LL, Taylor TR, et al. Functional characterization and haplotype analysis of polymorphisms in the human equilabrative nucleoside transporter, ENT2. Drug Metab. Dispos. 2006; 34:12-5.

Solute carrier family 29 member 2, Equilibrative nucleoside transporter 2, ENT2, DER12, HNP36

ELISA, WB, IHC-P, IF

38708299

Liquid