SLC2A4 Antilichaam - N-terminaal gebied: Biotine (ARP43785_P050-Biotine)

Solute carrier family 2 (facilitated glucose transporter), member 4

GLUT4

6517

P14672

NP_001033

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human SLC2A4

SLC2A4 is a member of the solute carrier family 2 (facilitated glucose transporter) family and functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus.This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM) . Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; FAR1; P3H1; FKBP10; ESYT2; GNL3L; CRNKL1; STRN3; ARFIP1; SDF2L1; P3H4; KLHL41; PDIA6; MVP; RAB7A; UBE2N; PSMD7; PRKAR1A; NSF; IDH1; HSP90AA1; HK2; GAPDH; DLD; CTSD; SERPINH1; BSG; ARF5; ARF3; ACTN1; ACTN4; ACOX1; DSK2; UBI4; C1QTNF5; MAP1S; EHD2; UBE

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

55kDa

McGee, S.L., (2008) Diabetes 57 (4), 860-867

Wet Ice

509

SLC2A4

SLC2A4

Rabbit

Solute carrier family 2, facilitated glucose transporter member 4

NM_001042

LQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALSV