SLC30A4 (NM 013309) Humaan Recombinant eiwit

Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450) . SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]) .[supplied by OMIM, Mar 2008]

Purified recombinant protein of Human solute carrier family 30 (zinc transporter), member 4 (SLC30A4), Pro336-Gln425, with N-terminal His-ABP tag, expressed in E. coli, 50ug

ZnT-4; ZNT4

7782

O14863

NM_013309

15q21.1

E. coli

N-His-ABP

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.

Transmembrane

25.3 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

SLC30A4

Human

NP_037441

https://www.ncbi.nlm.nih.gov/gene/7782

https://www.uniprot.org/uniprot/O14863

https://www.ncbi.nlm.nih.gov/nuccore/NM_013309

https://www.ncbi.nlm.nih.gov/nuccore/NP_037441