SLC9A3R1 Antilichaam

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

9368

O14745

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 189-358 of human SLC9A3R1 (NP_004243.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 50kDa

IgG

WB: 1:1000 - 1:4000

SLC9A3R1

293T

HT-29

MCF7

Mouse liver

Mouse kidney

Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1

Homo sapiens

SLC9A3R1, EBP50, NPHLOP2, NHERF, NHERF-1, NHERF1

WB

Liquid