SLCO1B1 Antilichaam - middengebied: Biotine (ARP43914_P050-Biotine)

Solute carrier organic anion transporter family, member 1B1

LST1, HBLRR, LST-1, OATP2, OATPC, OATP-C, OATP1B1, SLC21A6

10599

Q9Y6L6

NP_006437

Human, Cow, Pig

The immunogen is a synthetic peptide directed towards the middle region of human SLCO1B1

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Human: 100%; Pig: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

76kDa

Wet Ice

691

SLCO1B1

SLCO1B1

Rabbit

Solute carrier organic anion transporter family member 1B1

NM_006446

IILIYAMKKKYQEKDINASENGSVMDEANLESLNKNKHFVPSAGADSETH