SLF1081851
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SLF1081851 is a sphingosine-1-phosphate transporter (Spns2) inhibitor. It inhibited sphingosine-1-phosphate (S1P) release in HeLa cells: IC50 = 1.93 µM. SLF1081851 is active in vivo and decreased lymphocyte counts and plasma S1P levels in mice and rats. Spns2 inhibitors represent potential alternative immunomodulatory agents to S1P receptor agonists as they are able in induce lymphopenia without drastic changes to systemic S1P levels or stimulating the S1P1-5 signaling pathway.
Unconjugated
White solid
-20°C
Beschrijving
SLF1081851 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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