SLFN13 Antilichaam / Schlafen 13

Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. All members of the Schlafen family contain a conserved core domain and are substantially diversified at the N terminus. Changes in Schalfen protein expression may contribute to phenotypic differences seen in thymic subsets. Slfn13 (Schlafen family member 13), also known as SLFN10, is an 897 amino acid protein that exists as 2 alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 17q12.

Western blot: 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL

Q68D06

Human, Mouse, Rat

An E.coli-derived human recombinant protein (amino acids Q62-R797) was used as the immunogen for the Schlafen 13 antibody.

WB, ELISA

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Schlafen 13 antibody is available for research use only.

After reconstitution, the Schlafen 13 Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Schlafen 13 antibody should be determined by the researcher.

Western blot testing of human 1) HEL and 2) RT4 cell lysate with Schlafen 13 antibody. Predicted molecular weight ~102 kDa.