Slitrk2 Antilichaam

Slitrk2 Antibody: SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. Deletion analysis indicated that the functional difference between Slitrk2 and Slitrk1 is within their intracellular domains. At least two isoforms of this protein are known to exist.

84631

Q9H156

Q9H156

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Neuroscience

Slitrk2 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1463 - Rat Brain Tissue Lysate

1 mg/mL

Slitrk2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

Slitrk2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

SLITRK2

Cat. No. 10-301 - Human Brain Tissue Slide

SLIT and NTRK-like family, member 2

Homo sapiens

Aruga J and Mikoshiba K. Identification and characterization of Slitrk, a novel transmembrane protein family controlling neurite outgrowth. Mol. Cell Neurosci.2003; 24:117-29.

Aruga J, Yokota N, and Mikoshiba K. Human SLITRK family genes: genomic organization and expression profiling in normal and brain tumor tissue. Gene2003; 315:87-94.

Slitrk2 Antibody: CXorf2, SLITL1, CXorf2, KIAA1854, UNQ9197/PRO34756, SLIT and NTRK-like protein 2

ELISA, WB, IHC-P, IF

46397026

Liquid