SM-164
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Cell-permeable Smac (DIABLO) mimetic that inhibits caspase blockers XIAP, cIAP1, and cIAP2 (Ki = 36, <1, and <1.9 nM), thus inducing apoptosis.1-3 SM-164 sensitizes cancer cells to DNA damaging agents.4 It also prevents binding of Hsp70 to XIAP.5 At high concentrations, it causes lytic cell death that is neither apoptosis nor necroptosis.6
Unconjugated
White to pale-yellow solid
-20°C
Beschrijving
SM-164 Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
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