Smad2 (fosfo Thr220) Antilichaam

Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD) . May act as a tumor suppressor in colorectal carcinoma.

4087

Q15796

NP_001003652.1

Human, Mouse, Rat

Smad2 (Phospho-Thr220) antibody was raised against a peptide sequence around phosphorylation site of threonine 220 (P-E-T (p) -P-P) derived from Human Smad2.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

60 kDa

This antibody detects endogenous level of Smad2 only when phosphorylated at threonine 220.

Western Blot: 1:500~1:1000

SMAD2

SMAD family member 2

Homo sapiens

Sang Gyun Kim et al. (2004) Mol Biol Cell. February; 15 (2) : 420–434. Rebecca A. Randall et al. (2004) Mol Cell Biol. February; 24 (3) : 1106–1121. Kimberly A Brown et al. (2004) Breast Cancer Res. ; 6 (3) : R215–R231.

JV18, MADH2, MADR2, JV18-1, hMAD-2, hSMAD2, ERBB, ERBB1, HER1, Mad-related protein 2, Mothers against DPP homolog 2

WB

51173730

Liquid