Smad3 (fosfo Thr179) Antilichaam

Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

4088

P84022

NP_001138574.1

Human, Mouse, Rat

Smad3 (phospho Thr179) antibody was raised against a peptide sequence around phosphorylation site of threonine179 (P-E-T (p) -P-P) derived from Human Smad3 .

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

50 kDa

IgG

The antibody detects endogenous level of Smad3 only when phosphorylated at threonine 179.

Western Blot: 1:500~1:1000

SMAD3

SMAD family member 3

Homo sapiens

Cohen-Solal KA, et al. (2011) Pigment Cell Melanoma Res 24, 512-24

Zelivianski S, Cooley A, Kall R, Jeruss JS (2010) Mol

Cancer Res 8, 1375-87

Matsuura I, et al. (2010) J Biol Chem 285, 1754-64

JV15-2, MAD-3, MADH3, Smad 3, Mothers against decapentaplegic homolog 3

WB

223029440

Liquid