SMAD3 Proteïne, Human, Mouse, Rat, Recombinant (His & GST)
Gecertificeerd

SMAD3 Proteïne, Human, Mouse, Rat, Recombinant (His & GST)

Catalog #: TMPY-03419-01
Maat: 5 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Bioactivity

SMAD3 belongs to the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD3 is involved in cell signalling. It modulates signals of activin and TGFβ's. Binding of SMAD3 with SMAD4 enables its transmigration into the nucleus where it forms complexes with other proteins and acts as a transcription factor. SMAD3 is a receptor-regulated SMAD (R-SMAD) . In mice, mutation of SMAD3 has been linked to colorectal adenocarcinoma, increased systemic inflammation, and accelerated wound healing. Increased SMAD3 activity has been implicated in the pathogenesis of scleroderma. Smad3 is also a multifaceted regulator in adipose physiology and the pathogenesis of obesity and type 2 diabetes.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

SMAD3 Proteïne, Human, Mouse, Rat, Recombinant (His & GST) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamSMAD3 Proteïne, Human, Mouse, Rat, Recombinant (His & GST)
Categorie
Beschikbare grootte5 µg
CatalogusnummerTMPY-03419-01