SMAD3-S208 Antilichaam

SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

4088

P84022

P84022

Human, Mouse

This SMAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from human SMAD3.

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Rat, Pig, Chicken

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

48 kDa

Rabbit Ig

SMAD3

Mothers against decapentaplegic homolog 3

Homo sapiens

Zhang, M., et al. J. Biol. Chem. 285 (12) :8703-8710 (2010)

Daly, A.C., et al. J. Biol. Chem. 285 (9) :6489-6497 (2010)

Heikkinen, P.T., et al. J. Biol. Chem. 285 (6) :3740-3749 (2010)

Tseng, Z.H., et al. Heart Rhythm 6 (12) :1745-1750 (2009)

Mothers against decapentaplegic homolog 3, MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3, JV15-2, SMAD family member 3, SMAD 3, Smad3, hSMAD3, SMAD3, MADH3

WB, IHC-P, IF, Flow

51338669

Liquid