SMAD6-eiwit, menselijk, recombinant (E. coli, His & Myc)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Transforming growth factor-beta superfamily receptors signaling occurs through the Smad family of intracellular mediators. SMAD6 is an inhibitory Smad (i-Smad) that negatively regulates signaling downstream of type I transforming growth factor-beta. Acts as a mediator of TGF-beta and BMP anti-inflammatory activities. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. Blocks the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions.
Ice Packs
-20°C
Beschrijving
SMAD6-eiwit, menselijk, recombinant (E. coli, His & Myc) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
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