SMARCA2 Antilichaam - middelste regio : HRP (ARP34484_P050-HRP)

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 and 4

BRM, SNF2, SWI2, hBRM, NCBRS, Sth1p, BAF190, SNF2L2, SNF2LA, hSNF2a

6595; 6597

P51531P51532

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SMARCA2

SMARCA2 is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

SDCBP; BEND7; UBC; SMURF2; EED; BMI1; SOX2; UL29; tat; SS18; SSX2; EPAS1; ARID1A; CBX5; PSMB2; ACTL6A; ARID1B; SEPT11; PHF10; NCOR1; SEC22B; SLC9A3R2; TOP2B; SMARCE1; SMARCD3; SMARCD2; SMARCD1; SMARCC2; SMARCC1; SMARCB1; SMARCA4; BMX; CEBPB; SIRT7; DPF1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

32kDa

Muchardt, C., et al., (1994) Mamm. Genome 5 (4), 241-242

Wet Ice

100% homologous to both isoforms of SMARCA2 and all 5 isoforms of SMARCA4

278

SMARCA2

SMARCA2

Rabbit

VINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKY