SMARCE1 Antilichaam, KO gevalideerd

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

6605

Q969G3

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-411 of human SMARCE1 (NP_003070.3) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Other

Affinity purification

U-251MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 55kDa

IgG

SMARCE1

MCF-7

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1

Homo sapiens

SMARCE1, BAF57

WB, IHC, IF, IP

Liquid