SMC2 Antilichaam - middengebied: HRP (ARP46156 P050-HRP)

Structural maintenance of chromosomes 2

CAPE, CAP-E, SMC-2, SMC2L1

10592

O95347

NP_006435

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SMC2

SMC2 belongs to the SMC family. It is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

UBC; RPA3; RPA2; RPA1; NCAPG; CCAR2; NCAPH; SSSCA1; SMC4; NCAPD2; PLEC; CDK9; FBXO6; EGFR; SOX2; GULP1; ABCC5; PAXIP1; SMC1A; UBD; NEDD8; SUMO2; NCAPG2; NCAPH2; NCAPD3; RAD21; LIG4; HIST2H3C; DISC1; TRAF3IP1; HIST2H2BE; HIST2H2AC; H2AFZ; MYC; tat; DNMT3B

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

136kDa

Ham, M.F., (2007) Cancer Sci. 98 (7), 1041-1047

Wet Ice

1197

SMC2

SMC2

Rabbit

Structural maintenance of chromosomes protein 2

NM_006444

ATLAGQMMACKNDISKAQTEAKQAQMKLKHAQQELKNKQAEVKKMDSGYR