SMC4 Antilichaam - middengebied: Biotine (ARP46131_P050-Biotine)

Structural maintenance of chromosomes 4

CAPC, CAP-C, SMC-4, SMC4L1

10051

Q9NTJ3

NP_001002800

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SMC4

SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

UBC; SUMO2; LGR4; RPA3; RPA2; RPA1; RNF2; NCAPH; SMC2; SSSCA1; NCAPD2; TBC1D4; PLEC; AP3S1; CDK9; NCAPG; CCAR2; RABL6; TOPBP1; FBXO6; UBD; HDAC11; MYC; Nfe2l2; NEDD8; CDK2; SIRT7; NCAPH2; NCAPD3; RAD21; TRAF3IP1; SUMO1; HDAC1; tat; DNMT3B

Biotin

Polyclonal Antibody

WB

Affinity Purified

There is BioGPS gene expression data showing that SMC4 is expressed in MCF7

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

147kDa

Ham, M.F., (2007) Cancer Sci. 98 (7), 1041-1047

Wet Ice

1288

SMC4

SMC4

Rabbit

Structural maintenance of chromosomes protein 4

NM_001002800

EARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRK