SMG6 Antilichaam

This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.

23293

Q86US8

Human, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1419 of human SMG6 (NP_060045.4) .

Unconjugated

Primary Antibodies

Cancer

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 210kDa

IgG

WB: 1:500 - 1:2000

SMG6

Jurkat

SW620

Rat liver

SMG6 nonsense mediated mRNA decay factor

Homo sapiens

C17orf31, EST1A, SMG-6, hSMG5/7a, telomerase-binding protein EST1A, EST1 telomerase component homolog A, ever shorter telomeres 1A, smg-6 homolog, nonsense mediated mRNA decay factor, telomerase subunit EST1A

WB

Liquid