SMNDC1 Antilichaam - middengebied: Biotine (ARP40612 P050-Biotine)

Survival motor neuron domain containing 1

SMNR, SPF30, TDRD16C

10285

O75940

NP_005862

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SMNDC1

This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.

UBC; PRPF3; SF3B5; SND1; CUL3; SF3A2; ELAVL1; HIST3H3; mad2; KPNB1; SNRNP200; SNRPB; CDK5RAP3; PPAN; TSR1; RNMTL1; SF3B1; SF3B3; SF3B2; SF3A3; SF3B4; DDX21; RUVBL1; RPL3; FDFT1; EWSR1

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

27kDa

Little, J.T. (2008) J. Biol. Chem. 283 (13), 8145-8152

Wet Ice

238

SMNDC1

SMNDC1

Rabbit

Survival of motor neuron-related-splicing factor 30

NM_005871

QFNNRAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSK