SN-38
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Active metabolite of CPT-11 that inhibits DNA topoisomerase I (IC50 values are 0.74 and 1.9 μM in P388 and Ehrlich cells respectively) . Inhibits DNA and RNA synthesis (IC50 values are 0.077 and 1.3 μM respectively) but does not affect protein synthesis. Displays potent antitumor activity against a range of human tumor cell lines (IC50 values are 3.3, 13, 19 and 22 nM for HCT-116, BEL-7402, HL60 and HELA cells respectively) .
Unconjugated
Off-white solid
-20°C
Beschrijving
SN-38 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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