
SNAP-6201
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SNAP-6201 is a selective α1a adrenoceptor antagonist with a Ki of 0.2 nM. SNAP-6201 exhibits >1400-fold selectivity over α1b and α1d adrenoceptors. SNAP-6201 exhibits excellent selectively to inhibit intraurethral pressure (IUP) in the anesthetized dog model. SNAP-6201 can be used for benign prostatic hyperplasia (BPH) research[1].
252201-38-0
12352005
Adrenergic Receptor
GPCR/G Protein; Neuronal Signaling
Endocrinology
COC(C1(C2=CC=CC=C2)CCN(CCCNC(N3C(NC(CC)=C(C(N)=O)C3C4=CC(F)=C(F)C=C4)=O)=O)CC1)=O
C30H35F2N5O5
583.63
[1]Nagarathnam D, et al. Design and synthesis of novel alpha (1) (a) adrenoceptor-selective antagonists. 1. Structure-activity relationship in dihydropyrimidinones. J Med Chem. 1999 Nov 18;42 (23) :4764-77.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W724254/
Reference compound1
No Development Reported
α adrenergic receptor
Beschrijving
SNAP-6201 is a selective α1a adrenoceptor antagonist with a Ki of 0.2 nM. SNAP-6201 exhibits >1400-fold selectivity over α1b and α1d adrenoceptors. SNAP-6201 ex
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