SNAP25 Mouse Monoclonal Antibody [Kloon ID: LBI4G5]

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs) . The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) SNAP25 mouse monoclonal antibody, clone LBI4G5

BA416N4.2; dJ1068F16.2; RIC-4; RIC4; SEC9; SNAP; SNAP-25

Homo sapiens synaptosome associated protein 25 (SNAP25), transcript variant 1, mRNA.

6616

P60880

Unconjugated

SNARE interactions in vesicular transport

SNARE interactions in vesicular transport

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

SNAP25

https://www.ncbi.nlm.nih.gov/gene/?term=6616

https://www.uniprot.org/uniprot/P60880