SNCG Antilichaam [1H10D2]

SNCG (also designated gamma-synuclein or breast cancer-specific protein 1), with 127-amino acid protein (about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals, while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

6623

O76070

O76070

Human

Ni-NTA purified truncated recombinant SNCG expressed in E. Coli strain BL21 (DE3) .

1H10D2

Unconjugated

Primary Antibodies

Other

Antibody is purified by protein A affinity chromatography.

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

SNCG (breast cancer-specific protein 1) monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

SNCG

Synuclein, gamma (breast cancer-specific protein 1)

Homo sapiens

Haiyan Liu, Wei Liu, Yinwei Wu. Cancer Res. 2005 Sep 1;65 (17) :7635-43.

Rina Surgucheva , Belinda McMahon , Andrei Surguchov. Cell Motil Cytoskeleton. 2006 May 26.

BCSG1, PERSYN, PRSN, Breast cancer-specific gene 1 protein, SR, BCSG1

ELISA, WB, IHC

90110074