SND1 Antilichaam - N-terminal regio : HRP (ARP32563_T100-HRP)

Staphylococcal nuclease and tudor domain containing 1

P100, TDRD11, Tudor-SN

27044

Q7KZF4

NP_055205

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human SND1

SND1 was originally characterized as a transcriptional coactivator for Epstein-Barr virus nuclear antigen 2. It is a STAT6 TAD interacting protein containing staphylococcal nuclease (SN) -like domain and tudor domain. p100 . The interaction is mediated by the TAD domain of STAT6 and the SN-like domain of SND1. SND1 associates with the large subunit of RNA polymerase II and is mediating interaction between STAT6 and RNA polymerase II. It was identified as a novel coactivator for STAT6 and suggest its functions as a bridging factor between STAT6 and the basal transcription machinery

HUWE1; RAPGEF2; UBC; SUMO2; MDM2; LIN28A; SHFM1; DDX3X; EIF3CL; RPL35; RPS27; RPS26; RPS16; RPS11; RPS9; RPS6; RPS3A; RPS2; RPL23A; HNRNPU; TARDBP; UBD; RNU4-1; RNU5A-1; RNU6-1; PRPF8; RNU2-1; RNU1-1; G3BP1; VCAM1; MAK; ITGA4; FN1; CSNK2A1; SSR3; SRSF3; R

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB, IHC

SND1 is supported by BioGPS gene expression data to be expressed in Raji

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

100kDa

Yang, J., et al., (2002) EMBO J. 21 (18), 4950-4958

Wet Ice

885

SND1

SND1

Rabbit

Staphylococcal nuclease domain-containing protein 1

NM_014390

LPDYYLVTVMLSGIKCPTFRREADGSETPEPFAAEAKFFTESRLLQRDVQ