SnoN (SKIL) Mouse Monoclonal Antibody [Kloon ID: LBI2C9]

The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB) . In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Carrier-free (BSA/glycerol-free) SKIL mouse monoclonal antibody, clone LBI2C9

SNO; SnoA; SnoI; SnoN

Homo sapiens SKI like proto-oncogene (SKIL), transcript variant 1, mRNA.

6498

P12757

Unconjugated

WB 1:500, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

SKIL

https://www.ncbi.nlm.nih.gov/gene/?term=6498

https://www.uniprot.org/uniprot/P12757