SNOTAP

SNOTRAP (S-nitrosylation trapping by triaryl phosphine) is a chemical probe for S-nitrosylated (SNO) proteins. SNOTRAP based proteomic pipeline can identify 1181 SNO proteins (1714 SNO sites) in the brain of mouse models. SNOTRAP can be used for nitrosative stress related diseases such as neurodegenerative disease, endotoxic shock, cancer, multiple sclerosis, and sickle cell disease[1].

2080332-70-1

12352005

Biochemical Assay Reagents

Others

Cancer; Infection; Neurological Disease; Inflammation/Immunology; Cardiovascular Disease

P(C1=C(SC(CCOCCOCCOCCNC(CCCC[C@H]2[C@@]3([C@](CS2)(NC(=O)N3)[H])[H])=O)=O)C=CC=C1)(C4=CC=CC=C4)C5=CC=CC=C5

C37H46N3O6PS2

723.88

[1]Yang H, et al. An improved sulfur-nitroso-proteome strategy for global profiling of sulfur-nitrosylated proteins and sulfur-nitrosylation sites in mice. J Chromatogr A. 2023 Aug 30;1705:464162.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-D2902/

Dye Reagents

No Development Reported