SNRPB Antilichaam - middengebied: Biotine (ARP40443_P050-Biotine)

Small nuclear ribonucleoprotein polypeptides B and B1

COD, CCMS, SNRPB1, SmB/B', Sm-B/B', snRNP-B, SmB/SmB'

6628

Q66K91

NP_003082

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SNRPB

SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs) . These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

RFX6; KRT40; L3MBTL3; GOLGA2; DAB1; TRIM23; CEP55; BANP; SS18L1; TFIP11; RBPMS; CD2BP2; CALCOCO2; HUWE1; PNMA1; PSMA3; UBC; LIN28A; MEPCE; RPA3; RPA2; RPA1; SF3A3; NCS1; CDKN2A; SRPK3; PRPF4B; SRPK2; SKIV2L; ICAM1; CD81; IGSF8; PAN2; Snrpc; LSM8; SNRPD3

Biotin

Polyclonal Antibody

WB

Affinity Purified

SNRPB is strongly supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

24kDa

Ong, S.E., (2004) Nat. Methods 1 (2), 119-126

Wet Ice

231

SNRPB

SNRPB

Rabbit

Small nuclear ribonucleoprotein-associated protein PIRNR PIRNR037187

NM_003091

LRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMP