SNRPN-antilichaam

The small nuclear riboprotein-associated protein N (SNRPN) is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. SNRPN plays a role in pre-mRNA processing and alternative splicing (1) . SNRPN arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF) (2) . Mutations or deletions in the SNRPN gene may be linked to responsible for Angelman syndrome or Prader-Willi syndrome (3) .

6638

P63164

NP_003088

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

SNRPN antibody is affinity chromatography purified via peptide column.

Cat. No. 1208 - THP-1 Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (100%), Chicken: (95%)

SNRPN antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SNRPN antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

SNRPN antibody is human, mouse and rat reactive.

SNRPN

Cat. No. 10-901 - Human Spleen Tissue Slide

Small nuclear ribonucleoprotein polypeptide N

Homo sapiens

Ozcelik T, Leff S, Robinson W, et al. Small nuclear ribonucleoprotein polypeptide N (SNRPN), an expressed gene in the Prader-Willi syndrome critical region. Nat. Genet. 1992; 2:265-9.

Gray TA, Saitoh S, and Nicholls RD. An imprinted, mammalian bicistronic transcript encodes two independent proteins. Proc. Natl. Acad. Sci. USA 1999; 96:5616-21.

Chen Y, Liu YJ, Pei YF, et al. Copy number variations at the Prader-Willi syndrome region on chromosome 15 and associations with obesity in whites. Obesity 2011; 19:1229-34.

Small nuclear ribonucleoprotein-associated protein N, HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN, sm-N

ELISA, WB, IHC-P, IF

4507135

Liquid