SNX27 Antilichaam

SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain) . A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.

81609

Q96L92

Q96L92

Human

This SNX27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-340 amino acids from the Central region of human SNX27.

Unconjugated

Primary Antibodies

Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

61 kDa

Rabbit Ig

For WB starting dilution is: 1:1000

SNX27

Sorting nexin-27

Homo sapiens

Lunn, M.L., et al. Nat. Neurosci. 10 (10) :1249-1259 (2007)

Nassirpour, R., et al. Channels (Austin) 1 (5) :331-333 (2007)

MacNeil, A.J., et al. Biochem. Biophys. Res. Commun. 359 (4) :848-853 (2007)

Rincon, E., et al. Mol. Cell Proteomics 6 (6) :1073-1087 (2007)

Sorting nexin-27, SNX27, KIAA0488

WB

166214988

Liquid