SOCS3 Antilichaam

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN) -gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

9021

O14543

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human SOCS3 (NP_003946.3) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity, Obesity, Signal Transduction, Stem Cell

Affinity purification

Mouse spleen

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 30kDa

IgG

SOCS3

Suppressor of cytokine signaling 3

Homo sapiens

SOCS3, CIS3, Cish3, SSI-3, SOCS-3, suppressor of cytokine signaling 3, STAT induced STAT inhibitor 3, cytokine-induced SH2 protein 3, SSI3

WB, IHC, IF

Liquid