Sorafenib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
284461-73-0
NSC-724772, BAY 43-9006
C12661-20mg
Raf
MAPK
CNC (=O) C1=NC=CC (=C1) OC2=CC=C (C=C2) NC (=O) NC3=CC (=C (C=C3) Cl) C (F) (F) F
C21H16ClF3N4O3
Sorafenib is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.
2 years -80 in solvent
Beschrijving
Sorafenib Beschikbaar in 20 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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